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Extraordinarily Easy to use,  Modular HPLC

Each Merit system incorporates the proven, reliable, consistent, high specification, ultra-low drift and durable performance of the trusted Cecil pumps and UV/Visible detectors.  

Each system is fully PC controlled, using Merit software, to achieve and save high quality chromatograms.   Automatic integration is provided, without the need for  further baseline adjustment.  Qualitative work is remarkably easy. The fast checking of multi-component samples is easy.

System choices include a CE 4403 UV/Visible detector, a DAD WaveQuest detector, an isocratic CE 4401 pump, a CE 4402 binary pump and a column heater/chiller.  Biocompatible options are available.

Set-up of the system hardware is fast, the pump and detector  modules  each plug  into the USB ports of a PC or laptop.  The Merit software only takes a few seconds to load and  just a few minutes to master.  Save HPLC methods and store chromatograms within  Merit software or elsewhere on the PC , network or portable drive etc.  

In the case of the Merit PC software,  chromatograms may be copied and pasted into other software programmes, such as Word or PowerPoint.  

All the numerical data points captured within each chromatogram is saved.  In two key strokes, data may be manually copied and pasted into Excel or other software spreadsheets.  

GLP data such as time, date, serial number of the detector etc. are automatically displayed.  Again, data may be copied and pasted into Word, PowerPoint or other software packages.

In addition, the Merit software contains a spacious  library.  Once a chromatogram is created, it may be saved into the library.  In two clicks of the mouse, subsequent chromatograms, may then be compared with the saved chromatograms.  

When any two chromatograms are automatically compared with each other, a numerical match index is automatically created.  Within a few seconds, a league table of comparable chromatograms is created.  This is such a useful facility when performing initial method development and routine elutions.

The minimum PC requirements for Merit PC software are:-

• Personal Computer with Pentium class processor
• Pentium 200 MHz or better
• Microsoft Windows 95, 98, Me, 2000, NT, XP, 7, 8 or later
• Free hard-drive space required: 2 MB
• CD-ROM drive
• XGA or higher resolution monitor
• Monitor resolution 1024 x 768 or better
• Microsoft Mouse or compatible pointing device
• Two available USB ports

These Merit HPLC systems will make life so much easier for so many chemical, biological and materials analysts in so many fields. Multi compound screening scientists, scientists performing initial method development, production scientists, process development chemists, lecturers, teachers and novices, in fact everyone one who wants high impact quick and easy HPLC, will find that a Merit  is just right for their needs.  

The Merit HPLC systems demonstrate the ultimate in HPLC simplicity.  Just inject and go.

Merit HPLC Specifications

Isocratic HPLC Pump CE 4401

Flow Rate	0.001 to 10mL/min in 0.001 steps
Flow Reproducibility	Better than 0.1%
Maximum Pressure	40MPa = 400 bar
Over Pressure Cut-out	Adjustable between 3 and 40MPa
Low Pressure Cut-out	Adjustable between 0 and 40MPa
Material in contact with fluids	Ceramic inserts - biocompatible
	Check valves – ruby and sapphire
Pulsation	Better than ±0.5% at 2mL/min
PC connection	USB port

Binary Low Pressure Mixing HPLC Pump CE 4402

Flow Rate	0.001 to 10mL/min in 0.001/min increments
Pressure Range	0-40MPa over flow range
Flow Accuracy	<±0.5%
Flow Precision	<0.1% RSD
Pressure Pulsation	<±0.5% at 2mL/min
Gradient Forming	Binary gradient low pressure mixing and isocratic high pressure operation
Gradient Control	Using proprietary high-speed proportioning valves
Gradient Precision	Typically 0.2% RSD at 1mL/min
Material in contact with fluids	Ceramic inserts, ruby and sapphire check valves, PEEK
PC connection	USB port

UV-Visible Detector CE 4405

Optical System	Double beam with 1200 lines/mm grating monochromator
Wavelength Range	190-700nm
Wavelength Accuracy	± 1nm
Wavelength Precision	± 0.1nm
Optical Bandwidth	8nm
Straylight	< .02%, 220nm
Lamp	Deuterium lamp with elapsed time indicator
Absorbance Range	0.001 to 2A full scale in 11 ranges
Time Constant	0.1, 0.2, 0.5, 1, 2, 5 and 10 seconds
Method Storage	For up to 30 methods, security protected
Noise	± 1 x 10-5 A peak to peak, 220nm, 2s time constant
Drift	± 1 x 10-4 A/hour at constant temperature
Linearity	Better than 1%, 0.001 – 2A
Automatic Power-up/off	Pre-programmed top save warm-up time
Sample Flow Cell	8µL x 10mm pathlength
Refractive Index Sensitivity	< ± 5 x 10-4 A, water to methanol at 350nm
Flow Rate Sensitivity	< ± 3.5 x 10-3 A, for flow change 1-2mL/min, 300nm
PC connection	USB port

WaveQuest D.A.D. Ultra Fast Scanning Detector  CE 4403

Optical System	Double beam
Monochromator	With 1200 l/mm holographic grating
Wavelength Range	190-700nm
Optical Bandwidth	4nm – constant
Digital Resolution	1nm
Wavelength Accuracy	1nm
Wavelength Reproducibility	0.1nm
Absorbance Range	0 to 3A
Scan Speeds	Up to 1000nm/s
Baseline Flatness	± 0.002A over most of range
Straylight	<0.02% at 220nm and 340nm
Noise	< ±0.5 x 10–5 A at 230nm, 2s air test cell
Drift	< ±0.5 x 10–4 A at 230nm, using air test cell
Calibration and Test	Automatic at switch-on
Number of Peak Scans	Up to 100 peaks for any single elution
Multiple Scans of a Peak	Up to 8 scans of any peak
Scan Trigger	At start, set Absorbance value, point of inflection or at maximum
Scan Storage	Up to 100, password protected
Method Storage	Up to 30 methods, password protected

Heated Oven  CE 4407

Temperature Range	Ambient to 85ºC
Temperature and Set Point	3 digit bright LED display
Temperature Readout Resolution	0.1ºC
Temperature Stability	± 0.01ºC
Number of Columns	3 up to 25cm long with pre-columns
Heating Rate	30 mins to set point of 65ºC (ambient 25ºC)
Stabilising Time	Negligible when set point reached
Leak Detection	Vapour detector – adjustable shut down level

Autosampler  CE 4408

Carousel capacity	50 vials, 2mL
Loop sizes	10μL - 200μL
Injection valve	Rheodyne 7900-000
Sample loop flush	Operator selectable
Volume reproducibility	Better than 0.05%
Carry over (with wash)	Better than 0.005%
Replicate injection	up to 15
Cycle time	12s minimum

Solvent Degasser CE 4020

Number of flow channels	2
Maximum Flowrate	10mL/min
Materials Contacting Solvents	PEEK, glass filled PTFE, Teflon AF
Gas removal	To better than 1ppm at 1mL/min

Flow Rate	0.001 to 10mL/min in 0.001 steps
Flow Reproducibility	Better than 0.1%
Maximum Pressure	40MPa = 400 bar
Over Pressure Cut-out	Adjustable between 3 and 40MPa
Low Pressure Cut-out	Adjustable between 0 and 40MPa
Material in contact with fluids	Ceramic inserts - biocompatible
	Check valves – ruby and sapphire
Pulsation	Better than ±0.5% at 2mL/min
PC connection	USB port

Flow Rate	0.001 to 10mL/min in 0.001 steps
Flow Reproducibility	Better than 0.1%
Maximum Pressure	40MPa = 400 bar
Over Pressure Cut-out	Adjustable between 3 and 40MPa
Low Pressure Cut-out	Adjustable between 0 and 40MPa
Material in contact with fluids	Ceramic inserts - biocompatible
	Check valves – ruby and sapphire
Pulsation	Better than ±0.5% at 2mL/min
PC connection	USB port

====================================================

非常簡單易用，模塊化高效液相色譜法



每個(gè)優(yōu)點(diǎn)系統(tǒng)采用了經(jīng)過驗(yàn)證的，可靠的，一致的，高規(guī)格，超低漂移和信任塞西爾的耐用性能泵和紫外/可見光檢測器。

每個(gè)系統(tǒng)完全電腦控制，采用優(yōu)異的軟件，來實(shí)現(xiàn)和保存高質(zhì)量的色譜圖。自動(dòng)一體化設(shè)置，而不需要進(jìn)一步的基線調(diào)整。定性的工作是非常容易的。多組分樣品的快速的檢查也容易。

系統(tǒng)選擇包括CE 4403紫外/可見光檢測器，二極管陣列檢測器WaveQuest ，等度CE 4401泵， CE 4402二元泵和色譜柱加熱器/冷卻器。生物相容性可供選擇。

建立了系統(tǒng)的硬件速度快，泵和檢測每個(gè)模塊插入到PC或筆記本電腦的USB端口。優(yōu)異的軟件只需要幾秒鐘加載，只是幾分鐘的時(shí)間來掌握。保存的HPLC方法，并在優(yōu)異的軟件或PC ，網(wǎng)絡(luò)或可移動(dòng)驅(qū)動(dòng)器等其他地方商店色譜圖

在優(yōu)異的PC軟件的情況下，色譜圖可以復(fù)制并粘貼到其他軟件程序，如Word或PowerPoint 。

所有每個(gè)色譜圖中捕獲的數(shù)值數(shù)據(jù)點(diǎn)被保存。在兩個(gè)關(guān)鍵筆畫，數(shù)據(jù)可以手動(dòng)復(fù)制并粘貼到Excel或其他電子表格軟件。

GLP數(shù)據(jù)，如時(shí)間，日期，檢測器的序列號(hào)等被自動(dòng)顯示。同樣，數(shù)據(jù)可以被復(fù)制并粘貼到Word中， PowerPoint或其他軟件包。

此外，優(yōu)異的軟件包含了一個(gè)寬敞的圖書室。一旦色譜創(chuàng)建時(shí)，它可被保存到庫中。在兩次點(diǎn)擊鼠標(biāo)，則后續(xù)的色譜圖，然后可以與所保存的色譜圖相比較。

當(dāng)任意兩個(gè)色譜圖會(huì)自動(dòng)相互比較，數(shù)值匹配索引被自動(dòng)創(chuàng)建。幾秒鐘內(nèi)，可比較色譜圖的名次表被創(chuàng)建。這是多么有用的工具執(zhí)行初始方法開發(fā)和日常洗脫時(shí)。

為優(yōu)異的PC軟件的最低PC要求是： -
•個(gè)人電腦與奔騰級(jí)處理器
• Pentium 200 MHz或更好
•微軟Windows 95 ， 98 ， ME，2000 ， NT，XP ， 7 ， 8或更高版本
•所需的可用硬盤空間： 2 MB
• CD -ROM驅(qū)動(dòng)器
• XGA或更高分辨率的顯示器
•顯示器分辨率1024× 768或更高
• Microsoft鼠標(biāo)或兼容的指針設(shè)備
•兩個(gè)可用的USB端口



這些優(yōu)異的HPLC系統(tǒng)將讓生活變得更輕松了這么多的化學(xué)，生物和材料分析在如此眾多的領(lǐng)域。多化合物篩選的科學(xué)家，執(zhí)行初始方法開發(fā)，生產(chǎn)的科學(xué)家，工藝開發(fā)的化學(xué)家，講師，教師和新手，其實(shí)大家一個(gè)誰愿意高抗沖快速簡便高效液相色譜科學(xué)家，會(huì)發(fā)現(xiàn)一個(gè)優(yōu)點(diǎn)是正好適合他們的需求。

優(yōu)異的HPLC系統(tǒng)表現(xiàn)出極致的高效液相色譜法簡單。剛剛注入而歸。

技術(shù)規(guī)格：

等度HPLC泵CE 4401
流量0.001〜 10ml/min時(shí)0.001步驟
流量重復(fù)性優(yōu)于0.1％
最大壓力為40MPa = 400吧
過壓開孔可調(diào)節(jié)3至為40MPa
低壓切出可在0和為40MPa
材料與液體陶瓷刀片的接觸 - 生物相容性
止回閥 - 紅寶石和藍(lán)寶石
脈動(dòng)小于± 0.5 ％提升以2mL/min
PC連接USB端口

二元梯度混合HPLC泵CE 4402
流量0.001〜 10ml/min時(shí)在0.001/min增量
壓力范圍0 -為40MPa以上流量范圍
流量精度< ± 0.5 ％
流量精度< 0.1 ％RSD
以2mL/min壓力脈動(dòng)< ± 0.5 ％
梯度形成二元梯度低壓混合和等度高壓操作
梯度控制使用專有的高速比例閥
梯度精度一般為0.2 ％，相對標(biāo)準(zhǔn)偏差為1ml/min
材料與液體陶瓷刀片，紅寶石和藍(lán)寶石止回閥， PEEK接觸
PC連接USB端口